SILVERMARS® Medical Phosphorylcholine Coating Series
SILVERMARS® Medical Phosphorylcholine Coating is a functional surface modification used on intravascular and implantable medical devices to improve blood compatibility. By mimicking cell membrane, Silvermars phosphorylcholine coating forms a hydrophilic, antibiofouling layer that reduces blood clotting, protein adhesion, immune rejection, and bacterial attachment—enhancing the device’s biocompatibility and safety.
SILVERMARS® Medical Phosphorylcholine Coating Series
The SILVERMARS® antimicrobial polymer coatings are well-established medical coatings that mimic the outer layer of cell membranes, thereby inherently possessing biocompatibility and endowing the device surface with antithrombotic, anti-inflammatory, antimicrobial, and hydrophilic properties. We invite you to discover our comprehensive range of customized stent coating solutions designed to optimize clinical outcomes.
SILVERMARS® phosphorylcholine coating series meets diverse clinical needs:
M Series: applicable in a wide range of scenarios;
MP Series: plus version of M series, tailored for surfaces/structures with coating challenges;
MF Series: ideal for short-term implantation scenarios;
MH Series: hydrolysis-resistant, perfect for urological application scenarios.
SILVERMARS Phosphorylcholine Coating Product Introduction
The SILVERMARS® biomedical coatings series, built upon a 2‐Methacryloyloxyethyl Phosphorylcholine (MPC polymer), modifies medical device surfaces by leveraging their zwitterionic nature, which features an equal distribution of positive and negative charges within each molecule. As a biocompatible coating, it offers excellent antibiofouling capability, effectively resisting nonspecific adhesion of proteins, cells, and bacteria. By mimicking the natural structure of the cell membrane's outer leaflet, this advanced SILVERMARS® phosphorylcholine coating creates a highly lubricious and bio-inert surface that minimizes immune response and thrombosis.
SILVERMARS Phosphorylcholine Coatings Product Advantages
Bionic Structure Enhanced Biocompatibility:
Phosphorylcholine coating enhances compatibility, minimizing inflammatory response and device rejection.
Antifouling Properties:
Phosphorylcholine coating effectively resists nonspecific adsorption of proteins, cells, and bacteria.
By creating a biomimetic surface, our phosphorylcholine coating prevents coagulation and thrombosis formation.
Heparin-Sensitive Friendly:
Safe and compatible phosphorylcholine coating for individuals sensitive to heparin.
Strong Durability:
Ensures sustained and long-term phosphorylcholine coating performance via high durability.
Phosphorylcholine Coating: A Safer, More Cost-Effective Alternative to Heparin
|
Phosphorylcholine Coating
|
|
Heparin Coating
|
|
|
Molecular Structure
|
|
|
Physical Anticoagulation
|
Anticoagulation Principle
|
Drug - Based Anticoagulation
|
|
×
All individuals
|
Biological Rejection
Applicable Population
|
√
5% of Those Intolerant to Anti-
rejection Medications
|
|
Nanoscale
|
Synthesis Complexity
Coating Thickness
|
Micron - Scale
|
|
|
Coating Difficulty
|
|
|
Stable (Synthetic & Mass - produced)
|
Cost Stability
|
Unstable (Susceptible to
Raw Material Cost Volatility)
|
|
×
|
Overall Cost
Involvement of Drug -
Device Combination
|
√
|
|
|
Regulatory Approval Duration
for Related Products
|
|
SILVERMARS Phosphorylcholine Coatings Product Performance
Multi-Substrate Compatibility
Hemocompatibility
Protein Adhesion and Encrustation Resistance
Antimicrobial Activity
Nano-Scale Coating Thickness
SILVERMARS® Phosphorylcholine Coating Series Applications
Silvermars specializes in high-performance phosphorylcholine coating solutions specifically engineered for implantable and interventional medical devices necessitating properties like biomimicry, anticoagulation, anti-encrustation, and antifouling.
We can also offer kinds of anti thrombogenic coating and blood contact safe coating for sale, anything you need, please contact us.
hydrophilic surface modification
At Silvermars, we deliver high-performance hydrophilic surface modification solutions tailored for implantable and interventional medical devices. Our engineered hydrophilic layers rapidly form and retain a stable water-bound interface on device surfaces, reducing surface friction during insertion and navigation while supporting smooth, atraumatic handling. The modification is optimized to promote hemocompatibility, lower nonspecific protein adsorption, and help minimize adverse biological interactions that can compromise device performance or patient outcomes. Formulated for strong adhesion and long-term stability, our hydrophilic surface modification maintains consistent performance across relevant clinical use conditions, providing reliable support for devices that demand predictable, biocompatible surface behavior.
For devices that require precise intraoperative visualization under fluoroscopy or other imaging modalities, radiopacity enhancement ensures that the implant or catheter remains clearly discernible throughout the procedure, supporting accurate placement and reducing the need for repeated imaging. At the same time, the thromboresistant surface is engineered to resist platelet adhesion and activation at the blood–material interface, helping to preserve local hemodynamic stability and lower the risk of thrombus formation during prolonged blood contact. Together, these surface characteristics contribute to safer navigation, more reliable positioning, and improved overall performance in vascular and endovascular applications.
If you want to know more about antimicrobial polymer, please visit our website.
As a biomedical polymers inc focused on medical device surface modification solutions, we accompany clients from early-stage formulation screening through pilot scale-up and full production transfer, with dedicated technical support for process validation and regulatory documentation requirements. Our team works closely with each partner to adapt coating processes to existing manufacturing workflows, helping reduce development costs and shorten time-to-market while maintaining consistent coating performance across batches.
